Culture positive infection | |||||
---|---|---|---|---|---|
 | All | Early onset | Late Onset | Preterm | Term |
sICAM-1 | n = 40 | n = 5 | n = 35 | n = 33 | n = 7 |
AUC | 0.78 | 0.57 | 0.65 | 0.81 | 0.56 |
Optimum cut off | 249 ng/ml | 228 ng/ml | 504 ng/ml | 249 ng/ml | 170 ng/ml |
sensitivity | 77.5% | 40.0% | 48.6% | 87.9% | 71.4% |
specificity | 66.9% | 93.0% | 79.0% | 60.0% | 55.3% |
Positive predictive value | 38.7% | 25.0% | 56.7% | 39.7% | 22.7% |
Negative predictive value | 91.7% | 96.4% | 73.1% | 94.3% | 91.3% |
hsCRP | n = 40 | n = 6 | n = 34 | n = 32 | n = 8 |
AUC | 0.78 | 0.81 | 0.71 | 0.79 | 0.72 |
Optimum cut off | 0.6 mg/l | 0.6 mg/l | 0.6 mg/l | 0.6 mg/l | 0.4 mg/l |
sensitivity | 80% | 83.3% | 79.4% | 81.2% | 87.5% |
specificity | 71.4% | 80.2% | 59.0% | 73.6% | 59.5% |
Positive predictive value | 43.2% | 22.7% | 51.9% | 47.3% | 31.8% |
Negative predictive value | 92.9% | 98.6% | 83.7% | 93.1% | 95.7% |
SAA | n = 36 | n = 5 | n = 31 | n = 29 | n = 7 |
AUC | 0.68 | 0.74 | 0.67 | 0.68 | 0.65 |
Optimum cut off | 1 mg/l | 1 mg/l | 0.9 mg/l | 3 mg/l | 1 mg/l |
sensitivity | 63.9% | 80.0% | 77.4% | 41.4% | 85.7% |
specificity | 64.3% | 47.0% | 46.7% | 86.9% | 55.6% |
Positive predictive value | 31.1% | 12.5% | 42.9% | 46.2% | 27.3% |
Negative predictive value | 87.6% | 98.2% | 80.0% | 84.5% | 95.2% |
sE-selectin | n = 33 | n = 5 | n = 28 | n = 27 | n = 6 |
AUC | 0.72 | 0.77 | 0.66 | 0.79 | 0.52 |
Optimum cut off | 132 mg/l | 162 mg/l | 116 mg/l | 132 mg/l | 224 mg/l |
sensitivity | 63.6% | 60.0% | 67.9% | 66.7% | 33.3% |
specificity | 76.0% | 90.3% | 62.3% | 79.4% | 87.9% |
Positive predictive value | 41.2% | 30.0% | 48.7% | 48.6% | 40.0% |
Negative predictive value | 88.8% | 97.0% | 78.6% | 89.0% | 88.2% |