Table 6 Diagnostic performance of study measurements
Infected | |||||
|---|---|---|---|---|---|
| Â | All | Early onset | Late Onset | Preterm | Term |
sICAM-1 | n = 73 | n = 12 | n = 61 | n = 62 | n = 11 |
AUC | 0.79 | 0.56 | 0.66 | 0.80 | 0.65 |
Optimum cut off | 228 ng/ml | 228 ng/ml | 368 ng/ml | 228 ng/ml | 203 ng/ml |
sensitivity | 76.7% | 33.3% | 52.5% | 82.3% | 54.6% |
specificity | 75.6% | 95% | 72.2% | 70.4% | 82.4% |
Positive predictive value | 66.6% | 50.3% | 76.1% | 68.0% | 54.6% |
Negative predictive value | 83.6% | 90.35% | 47.4% | 83.8% | 82.4% |
hsCRP | n = 72 | n = 13 | n = 59 | n = 60 | n = 12 |
AUC | 0.73 | 0.74 | 0.64 | 0.73 | 0.78 |
Optimum cut off | 0.4 mg/l | 0.6 mg/l | 0.4 mg/l | 0.2 mg/l | 0.4 mg/l |
sensitivity | 69.4% | 61.5% | 71.2% | 75% | 83.3% |
specificity | 70.4% | 82.3% | 55.6% | 65.6% | 63.6% |
Positive predictive value | 59.5% | 36.3% | 71.2% | 61.4% | 45.4% |
Negative predictive value | 78.6% | 92.8% | 55.6% | 78.2% | 91.3% |
SAA | n = 68 | n = 12 | n = 56 | n = 57 | n = 11 |
AUC | 0.61 | 0.66 | 0.59 | 0.59 | 0.69 |
Optimum cut off | 1 mg/l | 1 mg/l | 3 mg/l | 5 mg/l | 1 mg/l |
sensitivity | 23.5% | 58.3% | 28.6% | 24.6% | 81.8% |
specificity | 92.8% | 67.1% | 91.4% | 92.4% | 59.4% |
Positive predictive value | 66.6% | 21.8% | 84.2% | 70.0% | 40.9% |
Negative predictive value | 66.5% | 91.1% | 44.5% | 62.9% | 90.5% |
sE-selectin | n = 62 | n = 12 | n = 50 | n = 52 | n = 10 |
AUC | 0.72 | 0.69 | 0.67 | 0.77 | 0.65 |
Optimum cut off | 132 mg/l | 161.7 mg/l | 91.5 mg/l | 91.5 mg/l | 204 mg/l |
sensitivity | 54.8% | 50.0% | 71.2% | 78.9% | 50.0% |
specificity | 82.3% | 93.9% | 54.8% | 67.2% | 93.1% |
Positive predictive value | 66.6% | 60.2% | 71.7% | 65.1% | 71.3% |
Negative predictive value | 73.8% | 91.0% | 54.1% | 80.4% | 84.4% |