A prospective study of the sensitivity, specificity and diagnostic performance of soluble intercellular adhesion molecule 1, highly sensitive C-reactive protein, soluble E-selectin and serum amyloid A in the diagnosis of neonatal infection

Table 1 Gestational age & diagnosis requiring care in NICU

Diagnosis	Infected (n = 74)	Not Infected (n = 114)	Controls (n = 27)
Prematurity/LBW/VLBW/IUGR	33	65	17
Respiratory difficulty (pneumonia, RDS, TTN, BPD, asphyxia, pneumothorax)	23	44	5
NEC/GI obstruction/seizures/jaundice/skin necrosis	7	7	0
Congenital malformation	7	3	3
Suspected infection	17	4	0
Peri-operative care	3	3	0
Haemorrhage/circulatory disturbance (shock, APH, PIH, dehydration, twin-twin transfusion)	0	11	2
PROM, meconium staining, Placenta praevia	11	14	0
Gestational Age
Median	29.0	32.0	32.0
25^th quartile	27.0	29.0	28.25
75^th quartile	35.0	36.0	34.0

Abbreviations:
RDS: respiratory distress syndrome, NEC: necrotising enterocolitis, PROM: premature rupture of membranes, TTN: transient tachypnoea of the newborn, VLBW: very low birth weight, BPD: bronchopulmonary dysplasia, IUGR: intrauterine growth retardation, PIE: pulmonary interstitial emphysema, APH:ante partum haemorrhage, PIH: primary intracerebral haemorrhage

ISSN: 1471-2431