Table 2 Comparison of hydrocephalus CSF samples grouped according to clinical characteristics
Congenital | Acquired | p | |
|---|---|---|---|
n | 30 | 35 | |
Age (years) | 0.35 (0 – 14.3) | 0.4 (0 – 11.2) | > 0.1 |
Protein (mg/dL) | 271 (36–853) | 203 (14 – 1284) | > 0.1 |
NGF (pg/mL) | 149 (< 1 – 2025) | 238 (< 1 – 1876) | > 0.1 |
NGF/protein ratio | 1.03 (0.04 – 14.82) | 1.04 (0.05 – 59.09) | > 0.1 |
Low NGF (< 10 pg/mL) | 5 (17 %) | 4 (11 %) | > 0.1 |
Undetectable NT-3 | 6 /17 | 11 /14 | 0.029 |
Cultures positive | Cultures negative | p | |
n | 8 | 57 | |
Age (years) | 0.35 (0.1 – 2.4) | 0.4 (0 – 14.3) | > 0.1 |
Protein (mg/dL) | 241 (88 – 1100) | 248 (14 – 1284) | > 0.1 |
NGF (pg/mL) | 473 (43 – 2025) | 200 (< 1 – 1876) | > 0.1 |
NGF/protein ratio | 0.96 (0.20 – 7.47) | 1.04 (0.04 – 59.09) | > 0.1 |
Low NGF (< 10 pg/mL) | 0 (0 %) | 9 (16 %) | > 0.1 |
Undetectable NT-3 | 2 /2 | 15 /29 | > 0.1 |
First sample | Repeat sample | p | |
n | 42 | 23 | |
Age (years) | 0.4 (0 – 14.3) | 0.3 (0 – 11.2) | > 0.1 |
Protein (mg/dL) | 251 (15 – 1100) | 210 (14 – 1284) | > 0.1 |
NGF (pg/mL) | 149 (<1 – 2025) | 279 (< 1 – 1876) | > 0.1 |
NGF/protein ratio | 0.98 (0.07 – 59.09) | 1.07 (0.04 – 16.43) | > 0.1 |
Low NGF (< 10 pg/mL) | 7 (17 %) | 2 (9 %) | > 0.1 |
Undetectable NT-3 | 9 /19 | 8 /12 | > 0.1 |
Pressure low | Pressure elevated | p | |
n | 7 | 58 | |
Age (years) | 1.1 (0.1 – 4.8) | 0.3 (0 – 14.3) | > 0.1 |
Protein (mg/dL) | 149 (15 – 467) | 253 (14 – 1284) | > 0.1 |
NGF (pg/mL) | 87 (< 1 – 886) | 234 (< – 2025) | > 0.1 |
NGF/protein ratio | 0.50 (0.20 – 59.09) | 1.07 (0.04 – 16.43) | > 0.1 |
Low NGF (< 10 pg/mL) | 1 (14 %) | 8 (14 %) | > 0.1 |
Undetectable NT-3 | 2 /3 | 15 /28 | > 0.1 |