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  1. Research article

    Molecular epidemiology of Rotavirus causing diarrhea among children less than five years of age visiting national level children hospitals, Nepal

    Rotaviruses are the major cause of diarrhea among the infants and young children all over the world causing over 500,000 deaths and 2.4 million hospitalizations each year. In Nepal Rotavirus infection positivi...

    Subhash Dhital, Jeevan Bahadur Sherchand, Bharat Mani Pokhrel, Keshab Parajuli, Niranjan Shah, Shyam Kumar Mishra, Sangita Sharma, Hari Prasad Kattel, Sundar Khadka, Sulochana Khatiwada, Narayan Parajuli and Basistha Rijal

    BMC Pediatrics 2017 17:101

    Published on: 7 April 2017

  2. Technical advance

    Simultaneous detection of respiratory syncytial virus and human metapneumovirus by one-step multiplex real-time RT-PCR in patients with respiratory symptoms

    Both respiratory syncytial virus (RSV) and human metapneumovirus (hMPV) are important viral pathogens causing respiratory tract infection (RTI) in the pediatric population. However, the clinical manifestations...

    Huey-Ling You, Shun-Jen Chang, Hong-Ren Yu, Chia-Chin Li, Chang-Han Chen and Wei-Ting Liao

    BMC Pediatrics 2017 17:89

    Published on: 27 March 2017

  3. Research article

    Reduced PRF1 enhancer methylation in children with a history of severe RSV bronchiolitis in infancy: an association study

    Acute lower respiratory tract infection is the commonest disease affecting children under five worldwide. Respiratory syncytial virus (RSV) is among the most common causative pathogens. Epidemiological data su...

    Magdeldin Elgizouli, Chad Logan, Ruth Grychtol, Dietrich Rothenbacher, Alexandra Nieters and Andrea Heinzmann

    BMC Pediatrics 2017 17:65

    Published on: 3 March 2017

  4. Research article

    Efficacy, safety and effectiveness of licensed rotavirus vaccines: a systematic review and meta-analysis for Latin America and the Caribbean

    RotaTeq™ (RV5; Merck & Co. Inc., USA) and Rotarix™ (RV1, GlaxoSmithKline, Belgium) vaccines, developed to prevent rotavirus diarrhea in children under five years old, were both introdu...

    Raúl F. Velázquez, Alexandre C. Linhares, Sergio Muñoz, Pamela Seron, Pedro Lorca, Rodrigo DeAntonio and Eduardo Ortega-Barria

    BMC Pediatrics 2017 17:14

    Published on: 13 January 2017

  5. Research article

    Exploring neurodevelopmental outcome measures used in children with cerebral malaria: the perspectives of caregivers and health workers in Malawi

    Progress has been made in tackling malaria however there are still over 207 million cases worldwide, the majority in children. As survival rates improve, numbers of children with long-term neurodisabling seque...

    Emmie W. Mbale, Terrie Taylor, Bernard Brabin, Macpherson Mallewa and Melissa Gladstone

    BMC Pediatrics 2017 17:9

    Published on: 10 January 2017

  6. Research article

    Surgical antibiotic prophylaxis in children: a mixed method study on healthcare professionals attitudes

    Qualitative and quantitative research investigating determinants of adherence to clinical guidelines (GLs) on surgical antibiotic prophylaxis (SAP) are scarce. We conducted a mixed-method study aimed at invest...

    Angela Giusti, Stefania Spila Alegiani, Marta Luisa Ciofi degli Atti, Sofia Colaceci, Roberto Raschetti, Pasquale Arace, Raffaele Spiazzi and Massimiliano Raponi

    BMC Pediatrics 2016 16:203

    Published on: 5 December 2016

  7. Research article

    An observational study of febrile seizures: the importance of viral infection and immunization

    Febrile seizures are common in young children. Annual peaks in incidence mirror increased respiratory virus activity during winter. Limited virological data are available using modern diagnostic techniques for...

    Joshua R. Francis, Peter Richmond, Christine Robins, Katie Lindsay, Avram Levy, Paul V. Effler, Meredith Borland and Christopher C. Blyth

    BMC Pediatrics 2016 16:202

    Published on: 3 December 2016

  8. Case report

    Development of rhabdomyolysis in a child after norovirus gastroenteritis

    In children, the most significant cause of rhabdomyolysis or muscle breakdown is viral infection. However, there are no reports that norovirus, a gastroenteric virus that commonly infects children, specificall...

    Tomohiro Nishio, Ryoko Yonetani, Eisuke Ito, Makiko Yoneta, Yoshihiro Maruo, Tokiko Yoshida and Tohru Sugimoto

    BMC Pediatrics 2016 16:176

    Published on: 4 November 2016

  9. Case report

    A case of Epstein-Barr virus–associated hemophagocytic lymphohistiocytosis with severe cardiac complications

    Hemophagocytic lymphohistiocytosis (HLH) is a life threatening hematological disorder associated with severe systemic inflammation caused by an uncontrolled and ineffective immune response resulting in cytokin...

    Yoshiki Kawamura, Hiroki Miura, Yuji Matsumoto, Hidetoshi Uchida, Kazuko Kudo, Tadayoshi Hata, Yoshinori Ito, Hiroshi Kimura and Tetsushi Yoshikawa

    BMC Pediatrics 2016 16:172

    Published on: 28 October 2016

  10. Research article

    Complicated norovirus infection and assessment of severity by a modified Vesikari disease score system in hospitalized children

    Norovirus (NoV) GII.4 is the most common genotype for norovirus gastroenteritis worldwide. New variants or subgenotypes are continuously emerging, thus posing a serious threat to child health.

    Pei-Lin Wang, Shih-Yen Chen, Chi-Neu Tsai, Hsun-Ching Chao, Ming-Wei Lai, Yi-Jung Chang, Chyi-Liang Chen and Cheng-Hsun Chiu

    BMC Pediatrics 2016 16:162

    Published on: 5 October 2016

  11. Research article

    Refractory wheezing in Chinese children under 3 years of age: bronchial inflammation and airway malformation

    Wheezing is a common symptom in early childhood. However, refractory wheezing is difficult to treat, and it may thus account for extensive use of medical resources. It is therefore important to improve our und...

    Wenjing Gu, Wujun Jiang, Xinxing Zhang, Zhengrong Chen, Yongdong Yan, Li Huang, Meijuan Wang, Xuejun Shao, Shuhui Wang and Wei Ji

    BMC Pediatrics 2016 16:145

    Published on: 27 August 2016

  12. Research article

    Compliance with the current recommendations for prescribing antibiotics for paediatric community-acquired pneumonia is improving: data from a prospective study in a French network

    Lower respiratory tract infection is a common cause of consultation and antibiotic prescription in paediatric practice. The misuse of antibiotics is a major cause of the emergence of multidrug-resistant bacter...

    Elise Launay, Karine Levieux, Corinne Levy, François Dubos, Alain Martinot, Bénédicte Vrignaud, Flora Lepage, Robert Cohen, Emmanuel Grimprel, Matthieu Hanf, François Angoulvant and Christèle Gras-Le Guen

    BMC Pediatrics 2016 16:126

    Published on: 12 August 2016

  13. Research article

    Health outcomes and the transition experience of HIV-infected adolescents after transfer to adult care in Québec, Canada

    Little is known on outcomes after transition to adult care among adolescents with perinatal HIV infection. Though there is data from other chronic pediatric diseases suggesting increased morbidity and mortalit...

    Fatima Kakkar, Dimitri Van der Linden, Silvie Valois, Francois Maurice, Marion Onnorouille, Normand Lapointe, Hugo Soudeyns and Valerie Lamarre

    BMC Pediatrics 2016 16:109

    Published on: 26 July 2016

  14. Research article

    Comparison of the frequency of bacterial and viral infections among children with community-acquired pneumonia hospitalized across distinct severity categories: a prospective cross-sectional study

    The comparison of the frequencies of bacterial and viral infections among children with community-acquired pneumonia (CAP) admitted in distinct severity categories, in an original study, is lacking in literatu...

    Amanda C. Nascimento-Carvalho, Olli Ruuskanen and Cristiana M. Nascimento-Carvalho

    BMC Pediatrics 2016 16:105

    Published on: 22 July 2016

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