General pediatric medicine and surgery

Section Edited by Kusum Menon

This section considers studies of general medicine and surgical intervention in children and adolescents.

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  1. Research article

    Relationship between Glycemic Levels and Treatment Outcome among Critically Ill Children admitted into Emergency Room in Enugu

    Critically ill children are those in need of immediate attention on arrival to an emergency room. The importance of glycemic level measurement as well as maintaining the patency of the airway, effective breath...

    Nwachinemere Davidson Uleanya, Elias Chikee Aniwada, Ikenna Chidiebele Nwokoye, Ikenna Kingsley Ndu and Christopher Bismarck Eke

    BMC Pediatrics 2017 17:126

    Published on: 16 May 2017

  2. Study protocol

    TropicALL study: Thromboprophylaxis in Children treated for Acute Lymphoblastic Leukemia with Low-molecular-weight heparin: a multicenter randomized controlled trial

    Venous thromboembolism (VTE) is a common and severe complication during treatment of acute lymphoblastic leukemia (ALL). An important cause is the intensive use of asparaginase. Prospective cohort studies in w...

    Irene L. M. Klaassen, Mandy N. Lauw, Marianne D. van de Wetering, Bart J. Biemond, Saskia Middeldorp, Floor C. H. Abbink, Marc Bierings, D. Maroeska M. W. te Loo, Rob Pieters, Inge M. van der Sluis, Wim J. E. Tissing, C. Michel Zwaan and C. Heleen van Ommen

    BMC Pediatrics 2017 17:122

    Published on: 10 May 2017

  3. Research article

    Does sevoflurane add to outpatient procedural sedation in children? A randomised clinical trial

    There is little evidence concerning the effect of sevoflurane in outpatient procedural sedation, especially in children. We hypothesised that the addition of sevoflurane to a sedation regimen improves children...

    Hugo Sérgio de Oliveira Gomes, Heloisa de Sousa Gomes, Joji Sado-Filho, Luciane Rezende Costa and Paulo Sucasas Costa

    BMC Pediatrics 2017 17:86

    Published on: 24 March 2017

  4. Research article

    Thermal quantitative sensory testing in healthy Dutch children and adolescents standardized test paradigm and Dutch reference values

    Quantitative sensory testing (QST) is often used to measure children’s and adults’ detection- and pain thresholds in a quantitative manner. In children especially the Thermal Sensory Analyzer (TSA-II) is often...

    Gerbrich E. van den Bosch, Monique van Dijk, Dick Tibboel and Abraham J. Valkenburg

    BMC Pediatrics 2017 17:77

    Published on: 16 March 2017

  5. Research article

    Evaluation of sublingual microcirculation in a paediatric intensive care unit: prospective observational study about its feasibility and utility

    Evaluation of the microcirculation in critically ill patients is usually done by means of indirect parameters. The aim of our study was to evaluate the functional state of the microcirculation by direct visual...

    Rafael González, Jorge López, Javier Urbano, María José Solana, Sarah Nicole Fernández, María José Santiago and Jesús López-Herce

    BMC Pediatrics 2017 17:75

    Published on: 15 March 2017

  6. Case report

    Carnitine-related hypoglycemia caused by 3 days of pivalate antibiotic therapy in a patient with severe muscular dystrophy: a case report

    Long-term treatment with antibiotics containing pivalic acid may decrease serum carnitine concentration and can sometimes be associated with severe hypoglycemia and encephalopathy in infants. Little has been r...

    Masanori Ito, Mitsumasa Fukuda, Yuka Suzuki, Hiroyuki Wakamoto and Eiichi Ishii

    BMC Pediatrics 2017 17:73

    Published on: 14 March 2017

  7. Research article

    Laparoscopic resection of neuroblastomas in low- to high-risk patients without image-defined risk factors is safe and feasible

    Several studies have reported that minimally invasive surgery (MIS) might be considered for resecting neuroblastomas without image-defined risk factors (IDRFs); however, there are no studies comparing the outc...

    Chiyoe Shirota, Takahisa Tainaka, Hiroo Uchida, Akinari Hinoki, Kosuke Chiba and Yujiro Tanaka

    BMC Pediatrics 2017 17:71

    Published on: 14 March 2017

  8. Research article

    Congenital malformations and medical conditions associated with orofacial clefts in children in Burkina Faso

    Orofacial clefts are usually isolated cases but can be associated with other congenital malformations that are either recognised or unrecognised syndromes. The reported prevalence and pattern of such associate...

    Kisito Nagalo, Isso Ouédraogo, Jean-Martin Laberge, Louise Caouette-Laberge and Jean Turgeon

    BMC Pediatrics 2017 17:72

    Published on: 14 March 2017

  9. Research article

    Premature atherosclerosis in children with beta-thalassemia major: New diagnostic marker

    Early vascular alteration, atherosclerosis and coronary artery disease have emerged as important cardiovascular complications among beta-thalassemia major (B-TM) patients. The aims of the current study were to...

    Laila M. Sherief, Osama Dawood, Adel Ali, Hanan S. Sherbiny, Naglaa M. Kamal, Mohamed Elshanshory, Osama Abd Alazez, Mohamed Abd Alhady, Mohamed Nour and Wesam A. Mokhtar

    BMC Pediatrics 2017 17:69

    Published on: 9 March 2017

  10. Debate

    Do systematic reviews on pediatric topics need special methodological considerations?

    Systematic reviews are key tools to enable decision making by healthcare providers and policymakers. Despite the availability of the evidence based Preferred Reporting Items for Systematic reviews and Meta-Analys...

    Mufiza Farid-Kapadia, Lisa Askie, Lisa Hartling, Despina Contopoulos-Ioannidis, Zulfiqar A. Bhutta, Roger Soll, David Moher and Martin Offringa

    BMC Pediatrics 2017 17:57

    Published on: 6 March 2017

  11. Study protocol

    Bell’s Palsy in Children (BellPIC): protocol for a multicentre, placebo-controlled randomized trial

    Bell’s palsy or acute idiopathic lower motor neurone facial paralysis is characterized by sudden onset paralysis or weakness of the muscles to one side of the face controlled by the facial nerve. While there i...

    Franz E. Babl, Mark T. Mackay, Meredith L. Borland, David W. Herd, Amit Kochar, Jason Hort, Arjun Rao, John A. Cheek, Jeremy Furyk, Lisa Barrow, Shane George, Michael Zhang, Kaya Gardiner, Katherine J. Lee, Andrew Davidson, Robert Berkowitz…

    BMC Pediatrics 2017 17:53

    Published on: 13 February 2017

  12. Research article

    A multicenter, randomized, open-label, active-comparator trial to determine the efficacy, safety, and pharmacokinetics of intravenous ibuprofen for treatment of fever in hospitalized pediatric patients

    Oral antipyretics are commonly used to treat pediatric patients who develop fevers. However, patients presenting to the emergency department or undergoing surgery are frequently unable to tolerate oral antipyr...

    Samia N. Khalil, Barry J. Hahn, Corrie E. Chumpitazi, Amy D. Rock, Byron A. Kaelin and Charles G. Macias

    BMC Pediatrics 2017 17:42

    Published on: 1 February 2017

  13. Research article

    Celiac disease and Down syndrome mortality: a nationwide cohort study

    Individuals with Down syndrome (DS) have increased mortality and are also at increased risk of celiac disease (CD). It is unknown if CD influences mortality in DS. In this study we examined the risk of death i...

    Jonas F. Ludvigsson, Benjamin Lebwohl, Peter H. R. Green, Wendy K. Chung and Karl Mårild

    BMC Pediatrics 2017 17:41

    Published on: 31 January 2017

  14. Research article

    MR imaging for detection of trampoline injuries in children

    The recreational use of trampolines is an increasingly popular activity among children and adolescents. Several studies reported about radiological findings in trampoline related injuries in children. The followi...

    E. Hauth, H. Jaeger, P. Luckey and M. Beer

    BMC Pediatrics 2017 17:27

    Published on: 18 January 2017

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